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Beilstein J. Org. Chem. 2018, 14, 2396–2403, doi:10.3762/bjoc.14.216
Graphical Abstract
Figure 1: a) Explosion was observed when an arylamine was mixed with aldehydes in the presence of IBX. b) Ben...
Figure 2: Comparison of the current work with the existing literature reports.
Figure 3: Synthesis of quinazolin-4(3H)-one derivatives from the reaction of 1 with liquid aldehydes. aYields...
Figure 4: Synthesis of quinazolin-4(3H)-one derivatives from reaction of 1 and solid aldehydes. aYields with ...
Figure 5: Crystal structure of 3a (CCDC No. 1823611).
Figure 6: Plausible mechanism for the quinazolin-4(3H)-ones synthesis using IBX.
Scheme 1: Large scale synthesis of 3a.